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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK25
All Species:
18.18
Human Site:
S355
Identified Species:
33.33
UniProt:
O00506
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00506
NP_006365.2
426
48112
S355
P
V
K
R
Q
P
R
S
Q
C
L
S
T
L
V
Chimpanzee
Pan troglodytes
XP_001162228
584
64501
S513
P
V
K
R
Q
P
R
S
Q
C
L
S
T
L
V
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
E405
Y
F
E
Q
K
E
K
E
N
Q
I
N
S
F
G
Dog
Lupus familis
XP_848578
318
35396
Q249
G
T
A
L
H
G
P
Q
K
S
A
E
P
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2W1
426
48157
S355
P
I
K
R
Q
P
R
S
Q
C
L
S
T
L
V
Rat
Rattus norvegicus
O54748
491
56103
N382
E
D
G
T
M
K
R
N
A
T
S
P
Q
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513191
426
48196
S355
P
I
K
R
Q
P
R
S
Q
C
L
S
T
L
V
Chicken
Gallus gallus
Q5ZJK4
486
55318
E404
Y
F
E
Q
K
A
K
E
N
Q
V
N
S
F
G
Frog
Xenopus laevis
Q6IP06
493
56486
S394
S
P
Q
G
P
R
P
S
F
M
D
Y
F
D
K
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
S387
S
M
R
R
N
P
T
S
Q
Q
I
Q
R
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
D449
T
T
A
K
N
N
D
D
Q
K
P
R
N
R
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
A402
P
S
K
N
Q
P
F
A
Q
D
G
T
G
P
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38692
1080
117043
S782
I
L
L
Q
P
L
N
S
I
P
S
S
S
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
38.4
71.5
N.A.
98.5
38.4
N.A.
94.3
38.8
38.5
38.6
N.A.
29.7
N.A.
35.6
N.A.
Protein Similarity:
100
72.5
57
72.5
N.A.
99.7
55.1
N.A.
97.8
55.9
56.1
56.9
N.A.
42.1
N.A.
51.7
N.A.
P-Site Identity:
100
100
0
0
N.A.
93.3
6.6
N.A.
93.3
0
6.6
26.6
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
46.6
13.3
N.A.
100
20
N.A.
100
46.6
13.3
46.6
N.A.
13.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
8
0
8
8
0
0
8
0
% D
% Glu:
8
0
16
0
0
8
0
16
0
0
0
8
0
0
0
% E
% Phe:
0
16
0
0
0
0
8
0
8
0
0
0
8
16
0
% F
% Gly:
8
0
8
8
0
8
0
0
0
0
8
0
8
0
16
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
0
0
0
0
0
8
0
16
0
0
0
0
% I
% Lys:
0
0
39
8
16
8
16
0
8
8
0
0
0
0
16
% K
% Leu:
0
8
8
8
0
8
0
0
0
0
31
0
0
31
8
% L
% Met:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
16
8
8
8
16
0
0
16
8
0
8
% N
% Pro:
39
8
0
0
16
47
16
0
0
8
8
8
8
16
0
% P
% Gln:
0
0
8
24
39
0
0
8
54
24
0
8
8
0
8
% Q
% Arg:
0
0
8
39
0
8
39
0
0
0
0
8
8
8
0
% R
% Ser:
16
8
0
0
0
0
0
54
0
8
16
39
24
0
8
% S
% Thr:
8
16
0
8
0
0
8
0
0
8
0
8
31
8
0
% T
% Val:
0
16
0
0
0
0
0
0
0
0
8
0
0
16
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _